Biofilm selection constitutively activates c-di-GMP synthesis by the bifunctional enzyme MbaA
Øyvind M. Lorentzen, Sören Abel, Pål Jarle Johnsen, Christopher Fröhlich
The paper identifies mutations in the enzyme MbaA that enhance c-di-GMP synthesis, promoting biofilm formation in Vibrio cholerae by disrupting polyamine regulation.
bioRxiv · Feb 13, 2025 · PreprintMicrobiology