Author

Leland L. Fleming

Harvard UniversityORCID 0000-0002-4047-9031Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:imaging· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:spatial domain detection· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Kristina VisscheriD· 2 shared Pınar DemirayakiD· 2 shared Dawn K. DeCarloiD· 1 shared Jennifer E. KhouryiD· 1 shared Karlen Lyons‐RuthiD· 1 shared Kerry James RessleriD· 1 shared Kyoko OhashiiD· 1 shared Martin H. TeicheriD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Kristina VisscherORCID

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3 papers

Recent·Most cited

Increased attentive use leads to more idiosyncratic functional connections

Pınar Demirayak, Leland L. Fleming, Paul Stewart, Rachel Chua, Kristina Visscher

The paper shows that increased attentive use of a brain region leads to more idiosyncratic functional connections, with implications for personalized rehabilitation and brain plasticity.

bioRxiv · Oct 15, 2025 · PreprintNeuroscience

Childhood Maltreatment and Brain Aging During Adulthood

Leland L. Fleming, Kyoko Ohashi, Michelle Bosquet Enlow, Jennifer E. Khoury, Torsten Klengel, Karlen Lyons‐Ruth, Martin H. Teicher, Kerry James Ressler

This study identifies specific types and ages of childhood maltreatment associated with accelerated brain aging in adulthood.

bioRxiv · Jan 16, 2025 · PreprintNeuroscience

Impact of deprivation and preferential usage on functional connectivity between early visual cortex and category-selective visual regions

Leland L. Fleming, Matthew K. Defenderfer, Pınar Demirayak, Paul Stewart, Dawn K. DeCarlo, Kristina Visscher

The paper examines how vision loss affects functional connectivity in early visual cortex, finding that spared peripheral regions show increased connectivity to motion-processing areas regardless of usage.

Human Brain Mapping · Nov 22, 2024Peer-reviewedNeuroscience