Luchang Zhu

Gene contribution of Streptococcus dysgalactiae subspecies equisimilis, an emerging pathogen, to experimental primate necrotizing myositis

This study identifies essential and conditionally essential genes in SDSE using TraDIS in vitro and in vivo, highlighting nutrient acquisition as critical for infection.

Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland,1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility

The paper analyzes whole genome sequencing data of macrolide-resistant Streptococcus pyogenes isolates in Iceland to identify clonal populations and resistance mechanisms.

Transcriptome remodeling contributes to epidemic disease caused by the human pathogen Streptococcus pyogenes

This study identifies horizontal gene transfer events in Streptococcus pyogenes that led to a more virulent genotype, causing epidemic disease through transcriptome remodeling and altered host-pathogen interactions.