Author

Jay Klievink

University of HelsinkiORCID 0000-0002-4081-5840Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Aleksandr IanevskiiD· 2 shared Diogo DiasiD· 2 shared Hanna LähteenmäkiiD· 2 shared Jonas BouhlaliD· 2 shared Olli DufvaiD· 2 shared Petra Johanna NygreniD· 2 shared Satu M. MustjokiiD· 2 shared Tero A. AittokallioiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Aleksandr IanevskiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Selective scoring of drug effects in multicellular co-culture systems

Diogo Dias, Aleksandr Ianevski, Jonas Bouhlal, Michele Ciboddo, Petra Johanna Nygren, Jay Klievink, Hanna Lähteenmäki, Olli Dufva, Satu M. Mustjoki, Tero A. Aittokallio

The paper introduces CES, a computational framework to score drug effects in multicellular co-culture systems, distinguishing between immunomodulatory effects and toxicity.

bioRxiv · May 24, 2026 · PreprintBioinformatics

Multimodal immunopharmacologic screens identify drugs rewiring the cancer-immune interface

Jonas Bouhlal, Emmi Jokinen, Petra Johanna Nygren, Diogo Dias, Aleksandr Ianevski, Jay Klievink, Hanna Lähteenmäki, Salomé Decombis, Hanna Duàn, Emmi Järvelä, Emma Saarinen, Anna Näätänen, Konstantin Matjusinski, Tiina Kasanen, Tiina Hannunen, , Satu M. Mustjoki

The paper identifies drugs that rewiring the cancer-immune interface by enhancing NK cell function and tumor susceptibility through multimodal screening approaches.

bioRxiv · Apr 17, 2026 · PreprintCancer Biology