Female Anterior Cruciate Ligaments Exhibit a Muted Mechanobiological Response to Mechanical Loading
Lauren Paschall, Maxwell A. Konnaris, Erdem D. Tabdanov, Aman Dhawan, Spencer E. Szczesny
This study investigates the impaired mechanobiological response of female ACLs to mechanical loading and finds fewer differentially expressed genes and enriched mechanotransduction pathways in females compared to males.
Journal of Orthopaedic Research® · Oct 15, 2025Peer-reviewedBioengineering