Maxwell A. Konnaris

This study identifies mechanotransduction pathways involved in chicken tendon development and shows how paralysis disrupts these processes.

This study investigates the impaired mechanobiological response of female ACLs to mechanical loading and finds fewer differentially expressed genes and enriched mechanotransduction pathways in females compared to males.

This paper shows Bayesian partially identified models outperform machine learning and normalization methods in microbiome data analysis by accounting for uncertainty in microbial load.

MPRAbase is a curated database of MPRA experiments that provides access to 17.7 million regulatory elements tested across 35 cell types and 4 organisms.

kmerDB provides a database of genomic and proteomic sequence information, including kmers, quasi-primes, and primes, for 45,785 genomes and 22,386 proteomes.

The paper calculates the rarity of short nucleic and peptide sequences across genomes and proteomes, finds dipeptide rarity in peptides but not dinucleotides, and develops predictive models for sequence frequency.

This paper introduces frequentmers, a metagenomic feature for early disease detection, and applies it to identify liver cirrhosis with high accuracy using stool samples.