Author

Matthias Kloor

German Cancer Research CenterORCID 0000-0002-4125-992XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

Aysel AhadovaiD· 2 shared Hans M. MorreauiD· 2 shared Maartje NielseniD· 2 shared Noah C. HeldermaniD· 2 shared Tom van WezeliD· 2 shared Anne-Sophie van der Werf – ′t Lam· 1 shared Diantha TerlouwiD· 1 shared Fabian StrobeliD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

Aysel AhadovaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Immunological profiles in Lynch syndrome colorectal cancers are not specific to mismatch repair gene defects

Noah C. Helderman, Marieke E. Ijsselsteijn, Madalina Cabuta, Manon van der Ploeg, Tom van Wezel, Aysel Ahadova, Matthias Kloor, Hans M. Morreau, Maartje Nielsen, Noel F.C.C. de Miranda

The paper examines immune profiles in Lynch syndrome colorectal cancers across different MMR gene defects and finds no significant differences in immunogenic features.

medRxiv · Aug 27, 2024 · PreprintGenetic & Genomic Medicine

Lower degree of microsatellite instability in colorectal carcinomas from MSH6-associated Lynch syndrome patients

Noah C. Helderman, Fabian Strobel, Lena Bohaumilitzky, Diantha Terlouw, Anne-Sophie van der Werf – ′t Lam, Tom van Wezel, Hans M. Morreau, Magnus von Knebel Doeberitz, Maartje Nielsen, Matthias Kloor, Aysel Ahadova

The paper compares microsatellite instability in colorectal carcinomas from MSH6-associated Lynch syndrome patients to other MMR-deficient groups and sporadic MSI CRCs, finding lower MSI in MSH6-mutated tumors.

bioRxiv · Aug 12, 2024 · PreprintGenetics