Author
Leiden University Medical CenterORCID 0000-0002-8090-8806Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Noah C. Helderman, Ting Yang, Claire Palles…·Margot Julia Wyrwoll
This study identifies biallelic germline variants in MCM8 and MCM9 as linked to polyposis, gastric cancer, early-onset colorectal cancer, and hypogonadism, with MCM9 variants showing stronger associations.
Diantha Terlouw, Manon Suerink, Yentl Buitelaar…·Maartje Nielsen
The paper identifies APC mosaicism in patients with colorectal adenomas, finds higher prevalence in those meeting hereditary polyposis guidelines, and recommends targeted testing and surveillance.
Noah C. Helderman, Fabian Strobel, Lena Bohaumilitzky…·Aysel Ahadova
The paper compares microsatellite instability in colorectal carcinomas from MSH6-associated Lynch syndrome patients to other MMR-deficient groups and sporadic MSI CRCs, finding lower MSI in MSH6-mutated tumors.