Tiled PCR amplification-based Whole Genome Sequencing and Phylogenetic Classification Accelerate the Implementation of Respiratory Syncytial Virus Genomic surveillance in Canada as a Pilot Study
Ruimin Gao, Cody J. Buchanan, Kerry Dust, Paul G. Van Caeseele, Henry Wong, Calvin P. Sjaarda, Prameet M. Sheth, Agatha N. Jassem, Jessica Minion, Nathalie Bastien
The paper develops tiled PCR assays for RSV whole genome sequencing, enabling high-throughput surveillance and improved phylogenetic analysis with more discriminatory mutations identified.
bioRxiv · Nov 22, 2024 · PreprintGenomics