BiochemistrybioRxivPreprint
Thiooxazole Formation on a Nontypeable Haemophilus influenzae Virulence Factor Requires a Mixed-Valent Diiron Cofactor
Olivia M. Manley, Madeline B. Ho, Patrick M McLean…·Amy C. Rosenzweig
This paper investigates the iron cofactor in the MNIO enzyme HvfB involved in oxazolin biosynthesis, revealing a mixed-valent diiron(II/III) cluster essential for 5-thiooxazole formation.
DOI 10.64898/2026.07.17.739211