Regularized logistic regression-based gene selection for functional analysis of heterogeneous scRNA-seq macrophage populations in muscle aging and regeneration.
Tiago L. Costa, Marta Belchior Lopes, Joana Neves…·Susana Vinga
The paper introduces DisTwiner, a method for subgroup-aware gene selection in scRNA-seq data, showing it captures biologically relevant aging pathways in macrophages.