Author

Patrick Page-McCaw

Vanderbilt UniversityORCID 0000-0002-4139-9770Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Organism:non-human primate· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Billy G. HudsoniD· 2 shared Carl E DarrisiD· 2 shared Julie K. HudsoniD· 2 shared Sergei P. BoudkoiD· 2 shared Aaron L. FidleriD· 1 shared Aspirnauts· 1 shared Bradley P. ClarkeiD· 1 shared Elena N. PokidyshevaiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMolecular Biology

Billy G. HudsonORCID

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2 papers

Recent·Most cited

Molecular BiologyJournal of Biological ChemistryPeer-reviewedMar 6, 2026

Collagen IV of basement membrane: V. Bromide-mediated sulfilimine bonds interlock the quaternary structure of NC1-hexamer of scaffolds enabling metazoan evolution.

Bradley P. Clarke, Vadim K. Pedchenko, Tetyana V. Pedchenko…·Billy G. Hudson

The paper shows that sulfilimine bonds stabilize the quaternary structure of Col-IV121 hexamers across species and that bromide-mediated bond formation is evolutionarily conserved.

1 citation

mousehuman

𝕏 PostBluesky

Evolutionary BiologybioRxivPreprintOct 18, 2023

Collagen IV of basement membranes: I. Origin and diversification of COL4 genes enabling animal evolution and adaptation

Patrick Page-McCaw, Elena N. Pokidysheva, Carl E Darris…·Billy G. Hudson

The paper investigates the evolutionary origin and diversification of collagen IV genes, revealing their role in the development of basement membranes and adaptation to environmental osmolarity.

3 citations

humancomparative / phylogenetic analysis

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