Author

Bradley P. Clarke

Vanderbilt UniversityORCID 0000-0002-9413-9905Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:human· 1 Organism:non-human primate· 1

Frequent Co-Authors

Billy G. HudsoniD· 2 shared Sergei P. BoudkoiD· 2 shared Alexia E AngelosiD· 1 shared Carl E DarrisiD· 1 shared Elena N. PokidyshevaiD· 1 shared Eric J. DelpireiD· 1 shared Gautam B. BhaveiD· 1 shared Jacob Edwards· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersMolecular Biology

Billy G. HudsonORCID

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Author profile →

3 papers

Recent·Most cited

Molecular BiologyJournal of Biological ChemistryPeer-reviewedMar 6, 2026

Collagen IV of basement membrane: V. Bromide-mediated sulfilimine bonds interlock the quaternary structure of NC1-hexamer of scaffolds enabling metazoan evolution.

Bradley P. Clarke, Vadim K. Pedchenko, Tetyana V. Pedchenko…·Billy G. Hudson

The paper shows that sulfilimine bonds stabilize the quaternary structure of Col-IV121 hexamers across species and that bromide-mediated bond formation is evolutionarily conserved.

1 citation

mousehuman

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Molecular BiologybioRxivPreprintFeb 25, 2026

An Alport variant illuminates the bioactivity of the collagen IV α565- α121 scaffold in Bowman's capsule.

Elena N. Pokidysheva, Rajan Koirala, Bradley P. Clarke…·Billy G. Hudson

The paper investigates the bioactivity of the collagen IV α565-α121 scaffold in Bowman's capsule by analyzing the effects of a Z-appendage variant in Col4a5.

DOI 10.64898/2026.02.23.707599

mousestatistical model

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Molecular BiologyeLifePeer-reviewedOct 27, 2023

Cryo-EM structure of the CBC-ALYREF complex

Bradley P. Clarke, Alexia E Angelos, Menghan Mei…·Yi Ren

The paper presents the cryo-EM structure of the CBC-ALYREF complex, revealing interactions between ALYREF and CBC subunits that contribute to mRNA export.

6 citations

protein structureexperimental assay

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