Author

Seishiro Hirano

National Institute for Environmental StudiesORCID 0000-0002-4148-0624Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1

Frequent Co-Authors

Osamu UdagawaiD· 3 shared Ayaka Kato-UdagawaiD· 1 shared Sanae KannoiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 2 mutual co-author links

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3 shared papersCell Biology

Osamu UdagawaORCID

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3 papers

Recent·Most cited

Biological differences in promyelocytic leukemia (PML) proteins between PML-nuclear bodies (PML-NBs) and extranuclear PML bodies (EnPBs) in arsenite-exposed cells.

Seishiro Hirano, Osamu Udagawa

This study examines how arsenite exposure affects PML protein solubility and SUMOylation, leading to changes in PML-NBs and EnPBs in cultured cells.

bioRxiv · Jan 26, 2026 · PreprintCell Biology

Formation of stress granules and non-canonical survival responses in arsenite-exposed cells.

Seishiro Hirano, Osamu Udagawa, Sanae Kanno

This study shows that arsenite induces stress granules and non-canonical survival responses in cells, with lower cytotoxicity at higher concentrations.

bioRxiv · Jul 29, 2024 · PreprintCell Biology

Promyelocytic leukemia nuclear body (PML-NB) -free intranuclear milieu facilitates development of oocytes in mice

Osamu Udagawa, Ayaka Kato-Udagawa, Seishiro Hirano

The paper shows that PML-NBs in oocytes sequester SUMO, affecting stress responses, and that a PML-NB-free environment preserves SUMO for oocyte development.

bioRxiv · Sep 6, 2021 · PreprintDevelopmental Biology