Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewed
Formation of amyloid loops in brain tissues is controlled by the flexibility of protofibril chains
Alyssa Miller, Jiapeng Wei, Sarah Meehan…·Tuomas P. J. Knowles
The paper investigates the formation of amyloid loops in brain tissues and finds that protofibril flexibility, not hydrogen bonding, enables loop formation and disease-related toxicity.
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