NeuroscienceMolecular NeurodegenerationPeer-reviewed
Oxidative Stress-Induced Microglial CD22 Upregulation Impairs Phagocytosis and Exacerbates Huntingtons Disease
Yan Hua Lee, Jian Jing Siew, Chia‐Wei Lee…·Yijuang Chern
This study identifies CD22 upregulation in microglia due to oxidative stress in HD, which impairs phagocytosis and worsens disease progression.
DOI 10.1186/s13024-026-00996-4