Author

Florence Solari

Lyon 1 UniversitéORCID 0000-0002-4173-8314Unclaimed ORCID profile · follow to get notified of new preprints

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Organism:C. elegans· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandre Pierre VaudanoiD· 1 shared Allan AlcoleiiD· 1 shared Charline RoyiD· 1 shared Christopher Neal· 1 shared Jean‐Louis BessereauiD· 1 shared L. Stojkovic· 1 shared Laurent Molin· 1 shared Laurent MouchiroudiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Alexandre Pierre VaudanoORCID

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2 papers

Recent·Most cited

A nuclear role for the contractile protein troponin I/UNC-27 in regulating muscle aging in C. elegans

Allan Alcolei, Manon Froment, Laurent Molin, Charline Roy, Romain Bulteau, Jean‐Louis Bessereau, Florence Solari

This study identifies a mutation in the troponin I gene unc-27 that delays muscle aging in C. elegans by altering its nuclear localization, preserving sarcomeric gene expression and delaying muscle decline.

bioRxiv · Aug 10, 2026 · PreprintCell Biology

MOSAIC: a longitudinal phenotypic clock to dissect organismal aging trajectories in C. elegans

Alexandre Pierre Vaudano, Marie Pierron, L. Stojkovic, Mathieu Membrez, Morgane Bourgeois, Christopher Neal, Myriam Chimen, Lina Verbakel, Matteo Cornaglia, Florence Solari, Laurent Mouchiroud

The paper develops MOSAIC, a non-invasive phenotypic clock for C. elegans that estimates biological age longitudinally and reveals distinct aging trajectories from lifespan interventions.

bioRxiv · Apr 27, 2026 · PreprintBioinformatics