Author

Joseph D. Locker

University of PittsburghORCID 0000-0002-4190-188XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Evan R. DelgadoiD· 2 shared Alejandro Soto–GutiérreziD· 1 shared Alina Ostrowska· 1 shared Andrew W. DuncaniD· 1 shared Bharat BhushaniD· 1 shared Bo Ram YangiD· 1 shared Frances AlencastroiD· 1 shared Kerollos KameliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Evan R. DelgadoORCID

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2 papers

Recent·Most cited

GeneticsCell Death and DiseasePeer-reviewedFeb 3, 2026

Diploid Hepatocytes Resist Acetaminophen-Induced Liver Injury Through Suppressed JNK Signaling

Sierra R. Wilson, Evan R. Delgado, Frances Alencastro…·Andrew W. Duncan

The paper shows diploid hepatocytes are more resistant to acetaminophen-induced liver injury due to reduced JNK signaling and mitochondrial damage.

1 citation

mousebulk RNA-seq

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PathologyFrontiers in GastroenterologyPeer-reviewedNov 12, 2024

A rat model of cirrhosis with well-differentiated hepatocellular carcinoma induced by thioacetamide

Zhiping Hu, Takeshi Kurihara, Yiyue Sun…·Evan R. Delgado

This study develops a rat model of cirrhosis-induced hepatocellular carcinoma using thioacetamide, showing fibrosis, altered liver architecture, and increased AFP levels.

2 citations

ratexperimental assay

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