Author

Nathan Diplock

Lawrence Livermore National LaboratoryORCID 0000-0002-4208-0892Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:machine learning (classical)· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

Christina S. Kang-YuniD· 1 shared Dan M. ParkiD· 1 shared Daniel J. WackeliniD· 1 shared Micaela FinneyiD· 1 shared Riyaz HaqueiD· 1 shared Sean P. LeonardiD· 1 shared Thomas DesautelsiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperSynthetic Biology

Christina S. Kang-YunORCID

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1 paper

Recent·Most cited

Unobserved Sequence Space Has Many Functional Proteins

Nathan Diplock, Thomas Desautels, Riyaz Haque, Micaela Finney, Daniel J. Wackelin, Christina S. Kang-Yun, Dan M. Park, Sean P. Leonard

The paper shows that unobserved protein sequence space contains many functional proteins, challenging the assumption that existing proteins cover most functional space.

bioRxiv · Aug 26, 2026 · PreprintSynthetic Biology