Author

Dianyu Chen

Westlake UniversityORCID 0000-0002-4217-2279Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Harinder SinghiD· 2 shared Heping XuiD· 2 shared Aly Azeem KhaniD· 1 shared Andrew SoniniD· 1 shared Bala RamaswamiiD· 1 shared David M. RothsteiniD· 1 shared Derek J. ReimaniD· 1 shared Godhev K. Manakkat VijayiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Harinder SinghORCID

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2 papers

Recent·Most cited

ImmunologyNature ImmunologyPeer-reviewedApr 20, 2026

BLIMP1 shapes germinal center B cell clonal diversity by gating chromatin accessibility during light-to-dark zone transition

Godhev K. Manakkat Vijay, Bala Ramaswami, Steven Gierlack…·Harinder Singh

This study shows Blimp1 restricts clonal dominance in germinal center B cells by controlling chromatin accessibility and BCR signaling during the light-to-dark zone transition.

DOI 10.1038/s41590-026-02495-6

mousescRNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintJun 26, 2020

Inferring cellular trajectories from scRNA-seq using Pseudocell Tracer

Derek J. Reiman, Heping Xu, Andrew Sonin…·Aly Azeem Khan

Pseudocell Tracer infers cellular trajectories from scRNA-seq data by simulating pseudocells in a virtual cell-state axis, revealing transcription factor dynamics during B cell immunoglobulin class switch recombination.

DOI 10.1101/2020.06.26.173179

humanscRNA-seq

𝕏 PostBluesky