Renal Interstitial Cells Promote Nephron Regeneration by Secreting Prostaglandin E2
Xiaoliang Liu, Ting Yu, Xiaoqin Tan, Daqing Jin, Wenmin Yang, Jiangping Zhang, Lu Dai, Zhongwei He, Dongliang Li, Yunfeng Zhang, Shuyi Liao, Jinghong Zhao, Tao P. Zhong, Chi Liu
The paper identifies renal interstitial cells (RICs) as key providers of a microenvironment for nephron regeneration in zebrafish, showing they secrete PGE2 to promote progenitor cell proliferation and nephron maturation.
eLife · Jan 16, 2023Peer-reviewedDevelopmental Biology