Tao P. Zhong

This paper introduces REDMAPCre, a red-light-activated Cre recombinase system that enables rapid and efficient DNA recombination in mammalian cells and mice.

The paper uses single-cell multi-omics to study early cardiac lineage specification in mouse embryos, identifying key transcription factors and regulatory networks.

The paper identifies renal interstitial cells (RICs) as key providers of a microenvironment for nephron regeneration in zebrafish, showing they secrete PGE2 to promote progenitor cell proliferation and nephron maturation.