Jamie McGowan

Long-read single-cell genomics: resolving chimeras in multiple displacement amplification

The paper develops lrSAGA, a tool to improve genome assembly from long-read MDA sequencing of single cells, achieving higher completeness and fewer misassemblies.

Single-cell sequencing reveals unexpected genetic diversity among Bodo spp. flagellates and their bacterial endosymbionts

The paper uses single-cell sequencing to reveal genetic diversity in Bodo flagellates and their bacterial endosymbionts, showing SSU rDNA is insufficient for species classification.

Multiple Independent Genetic Code Reassignments of the UAG Stop Codon in Phyllopharyngean Ciliates

The paper identifies multiple independent reassignments of the UAG stop codon to encode amino acids in Phyllopharyngean ciliates, showing UAG as a sense codon and UAA as the fixed stop codon.

Identification of a Non-Canonical Ciliate Nuclear Genetic Code Where UAA and UAG Code for Different Amino Acids

The paper identifies a non-canonical genetic code in a ciliate where UAA and UAG codons specify different amino acids, challenging the universality of the genetic code.