Surprising Phenotypic Diversity of Cancer-associated mutations of Gly 34 in the Histone H3 tail
Brandon R. Lowe, Rajesh Kumar Yadav, Ryan A. Henry, Patrick A. Schreiner, Atsushi Matsuda, Alfonso G. Fernandez, David Finkelstein, Margaret Campbell, Satish Kallappagoudar, Carolyn M. Jablonowski, Andrew J. Andrews, Yasushi Hiraoka, Janet F. Partridge
The paper shows that different mutations at Gly 34 of histone H3 cause distinct phenotypes in cancer, affecting DNA repair and genomic stability.
eLife · Feb 1, 2021Peer-reviewedMolecular Biology