The paper investigates the prevalence of ampicillin-susceptible Enterococcus faecium and E. lactis isolates with low cephalosporin MICs in Spain and Portugal, finding widespread occurrence and diverse genetic factors.

bioRxiv · Aug 28, 2026 · PreprintMicrobiology

Single point mutations in global regulatory genes restore cephalosporin resistance in a low-MIC Enterococcus faecium natural isolate

Miquel Sánchez−Osuna, Paula Bierge, Inmaculada Gómez-Sánchez, Judith Guitart-Matas, Víctor Monsálvez, Patricia Rabanal, Ana Paula Dier Pereira, Ana R. Freitas, Luísa Maria Sobreira Vieira Peixe, Mateu Espasa, Oriol Gasch, Carla Novais, Òscar Q. Pich

Antimicrobial Agents and Chemotherapy · Mar 23, 2026Peer-reviewedMicrobiology

Comparative mortality of dominant Staphylococcus aureus lineages in human bacteremia and animal infection models

Miquel Sánchez−Osuna, Marc Bravo, María-Alexandra Cañas, Andromeda-Celeste Gómez, Inmaculada Gómez-Sánchez, José María Miró, Isidre Gibert, Oriol Gasch, Cristina García de la Mària, Daniel Yero, Òscar Q. Pich

The paper compares the virulence of different Staphylococcus aureus lineages in bacteremia and infection models, finding significant differences in pathogenicity and identifying key virulence factors.

Microbial Pathogenesis · Jan 23, 2026Peer-reviewedMicrobiology

Genomic analysis of Staphylococcus aureus isolates from bacteremia reveals genetic features associated with the COVID-19 pandemic

Miquel Sánchez−Osuna, Marc Pedrosa, Paula Bierge, Inmaculada Gómez-Sánchez, Marina Alguacil-Guillén, Mateu Espasa, Ivan Erill, Oriol Gasch, Òscar Q. Pich

The paper analyzes S. aureus isolates from bacteremia to identify genetic features linked to the COVID-19 pandemic, finding increased prevalence of certain resistance genes and virulence factors.

iScience · Jun 28, 2024Peer-reviewedGenomics