Author

Emma M. Coomans

Amsterdam NeuroscienceORCID 0000-0002-4289-9101Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alida A. GouwiD· 1 shared Betty Marije TijmsiD· 1 shared Charlotte Elisabeth TeunisseniD· 1 shared Christa M. de GeusiD· 1 shared Elsmarieke van de GiesseniD· 1 shared Everard G.B. VijverbergiD· 1 shared Frederik BarkhofiD· 1 shared Georgii OzhegoviD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Alida A. GouwORCID

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1 paper

Recent·Most cited

TREM2 Risk Variants with Alzheimer Disease Differ in Rate of Cognitive Decline

Janna I.R. Dijkstra, Lisa Vermunt, Vikram Venkatraghavan, Georgii Ozhegov, Emma M. Coomans, Rik Ossenkoppele, Elsmarieke van de Giessen, Marc Hulsman, Christa M. de Geus, Wiesje M. van der Flier, Sietske A.M. Sikkes, Frederik Barkhof, Betty Marije Tijms, Alida A. Gouw, Willem de Haan, , Sven J. van der Lee

This study examines whether TREM2 risk variants in Alzheimer's disease patients lead to distinct clinical phenotypes, finding no baseline differences but faster cognitive decline in carriers.

Alzheimer s Research & Therapy · Mar 6, 2025Peer-reviewedGenetic & Genomic Medicine