Author

Andrew M. Scharenberg

Seattle Children's Research InstituteORCID 0000-0002-4292-6114Unclaimed ORCID profile · follow to get notified of new preprints

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Synthetic Biology· 1

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Anthony Nolan· 1 shared Barry L. StoddardiD· 1 shared Raymond J. MonnatiD· 1 shared

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2016-2016 · peak 1/yr

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1 shared paperSynthetic Biology

Anthony Nolan

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1 paper

Recent·Most cited

Synthetic BiologybioRxivPreprintNov 27, 2016

Retargeting: an unrecognized consideration in endonuclease-based gene drive biology

Andrew M. Scharenberg, Barry L. Stoddard, Raymond J. Monnat, Anthony Nolan

The paper examines how mutations during transcription and genome replication can affect HR-mediated gene drive systems based on different nuclease platforms, highlighting the risk of retargeting and the need for risk assessment.

5 citations

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