Author

Abba Μ. Krieger

University of PennsylvaniaORCID 0000-0002-4296-1278Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alex LashiD· 1 shared Andreas Buja· 1 shared Catherine LordiD· 1 shared Ivan H. IossifoviD· 1 shared Jianxin ShiiD· 1 shared Michael H. WigleriD· 1 shared Natalia VolfovskyiD· 1 shared Nilanjan ChatterjeeiD· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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1 shared paperGenetics

Alex LashORCID

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2 papers

Recent·Most cited

GeneticsProceedings of the National Academy of SciencesPeer-reviewedFeb 6, 2018

Damaging Mutations are Associated with Diminished Motor Skills and IQ in Children on the Autism Spectrum

Andreas Buja, Natalia Volfovsky, Abba Μ. Krieger…·Ivan H. Iossifov

The paper shows damaging de novo mutations in ASD are linked to impaired motor skills, independent of IQ, and proposes a new classification of phenotypic severity based on these associations.

64 citationstop 3%

humanstatistical model

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BioinformaticsJournal of the American Statistical AssociationPeer-reviewedSep 29, 2017

Post-selection Inference Following Aggregate Level Hypothesis Testing in Large Scale Genomic Data

Ruth Heller, Nilanjan Chatterjee, Abba Μ. Krieger, Jianxin Shi

The paper develops a framework for post-selection inference in genomic data to control false positive rates after class-level hypothesis testing, applied to eQTL analysis in 17 tissue types.

24 citations

humanwhole-genome sequencing

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