Phu V. Tran

Hierarchical Transcriptomic and Epigenetic Recovery and Remodeling in the Developing Hippocampus Following Early-life Environmental Insults: An Iron Deficiency Rat Model

This study examines transcriptomic and epigenetic changes in rat hippocampi after developmental iron deficiency and postnatal iron treatment, showing partial epigenetic recovery and new modifications.

Utility of brain-derived extracellular vesicles from human umbilical cord blood to measure non-infectious neuroinflammation and functional iron deficiency

This study isolates and analyzes brain-derived extracellular vesicles from umbilical cord blood to detect non-infectious neuroinflammation and neonatal iron deficiency in infants.

Transcriptional signatures in the rat medial prefrontal cortex associated with vulnerability and resilience across distinct phases of opioid use disorder

Sex-Specific Effects of Early-Life Iron Deficiency and Prenatal Choline Treatment on Adult Rat Hippocampal Transcriptome

This study examines sex-specific transcriptome changes in adult rat hippocampus due to early-life iron deficiency and prenatal choline treatment, finding greater effects in females.

ATAC and histone H3K9me3 landscapes revealed the altered epigenome by fetal-neonatal iron deficiency in the adult male rat hippocampus

This study examines how fetal-neonatal iron deficiency and prenatal choline supplementation affect epigenetic marks in adult rat hippocampi, revealing altered chromatin accessibility and H3K9me3 enrichment linked to gene dysregulation.

Repeated morphine exposure activates synaptogenesis and other neuroplasticity-related gene networks in the prefrontal cortex of male and female rats

This study identifies gene networks and pathways activated by repeated morphine exposure in rat prefrontal cortex, revealing sex-specific differences in neuroplasticity-related gene expression.