Author

Andrew C. Harris

University of MinnesotaORCID 0000-0001-8074-5464Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:rat· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Phu V. TraniD· 3 shared Shirelle X. LiuiD· 3 shared Aarthi RamakrishnaniD· 2 shared Jonathan C. Gewirtz· 2 shared Mark G. LeSage· 2 shared Peter Muelken· 2 shared Zia L. MaximiD· 2 shared Gerard Ahern· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Phu V. TranORCID

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4 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintOct 16, 2026

6-Methylnicotine is a strong agonist at α4β2 and α3β4 nicotinic cholinergic receptors

Thao T. Olson, Reniel Suarez Gonzalez, Yousef Aljohani…·Kenneth J. Kellar

This study compares 6-Methylnicotine and nicotine's effects on α4β2 and α3β4 nicotinic cholinergic receptors, finding 6-MN is more potent and upregulates these receptors.

DOI 10.64898/2026.10.09.757661

ratmouse

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PhysiologybioRxivPreprintApr 15, 2025

Utility of brain-derived extracellular vesicles from human umbilical cord blood to measure non-infectious neuroinflammation and functional iron deficiency

Phu V. Tran, Shirelle X. Liu, Andrew C. Harris…·Michael Georgieff

This study isolates and analyzes brain-derived extracellular vesicles from umbilical cord blood to detect non-infectious neuroinflammation and neonatal iron deficiency in infants.

2 citations

humanproteomics

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NeurosciencebioRxivPreprintFeb 29, 2024

Transcriptional signatures in the rat medial prefrontal cortex associated with vulnerability and resilience across distinct phases of opioid use disorder

Shirelle X. Liu, Peter Muelken, Zia L. Maxim…·Jonathan C. Gewirtz

DOI 10.1101/2024.02.29.582799

ratbulk RNA-seq

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NeuroscienceDrug and Alcohol DependencePeer-reviewedFeb 15, 2021

Repeated morphine exposure activates synaptogenesis and other neuroplasticity-related gene networks in the prefrontal cortex of male and female rats

Shirelle X. Liu, Mari S. Gades, Yayi Swain…·Jonathan C. Gewirtz

This study identifies gene networks and pathways activated by repeated morphine exposure in rat prefrontal cortex, revealing sex-specific differences in neuroplasticity-related gene expression.

29 citations

ratbulk RNA-seq

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