Folke Brinkmann

Fragmented gut-airway microbial networks and airway Moraxella clusters in preschool wheeze

This study compares nasal and stool bacterial communities in preschool wheezers and healthy controls, finding fragmented microbial networks and Moraxella enrichment in wheezers despite similar overall diversity.

scRNA-seq reveals persistent aberrant differentiation of nasal epithelium driven by TNFα and TGFβ in post-COVID syndrome

The paper uses scRNA-seq to identify aberrant differentiation in nasal epithelium of PCS patients, linking immune cell presence and inflammatory signaling to persistent symptoms.

Next-generation phenotyping integrated in a national framework for patients with ultra-rare disorders improves genetic diagnostics and yields new molecular findings

The paper evaluates a structured diagnostic framework for ultra-rare diseases, showing improved genetic diagnoses and novel gene-disease associations using exome sequencing and AI tools.