Markus Weckmann

The paper identifies a novel asthma-associated epithelial differentiation trajectory involving KRT14+ basal cells and hillock-like cells that contributes to airway inflammation and remodelling in childhood-onset asthma.

This study compares nasal and stool bacterial communities in preschool wheezers and healthy controls, finding fragmented microbial networks and Moraxella enrichment in wheezers despite similar overall diversity.

The paper uses scRNA-seq to identify aberrant differentiation in nasal epithelium of PCS patients, linking immune cell presence and inflammatory signaling to persistent symptoms.