Lars Bäckman

The paper shows two hippocampal integration dimensions persist across adulthood, relate to memory and dopamine distribution, and decline with age.

The paper investigates how reduced dopamine D1 receptor availability in aging is linked to decreased functional specificity in cortico-striatal circuits and poorer memory performance.

The paper uses deep learning to predict cognitive performance from functional connectomes during different brain states and identifies the brain-cognition gap as a dopamine-related marker of cognitive vulnerability.

The paper shows that dopamine D1 receptor organization in humans aligns with a unimodal-to-transmodal functional gradient and influences network differentiation and connectivity.

The paper investigates the relationship between brain iron levels and dopamine D1 receptors across the adult lifespan, finding that elevated iron and reduced D1DR in older adults correlate with impaired working memory.

The paper identifies a bi-phasic pattern of age-related dopamine D1 receptor decline, with distinct functional consequences before and after 40 years of age.

This study examines how neural variability during working memory is regulated by dopamine, functional integration, and decision-making using PET and fMRI data.