Robin Pedersen

This study compares brain organization during rest and naturalistic processing, finding greater functional gradient compression in older adults linked to worse cognitive performance.

The paper shows two hippocampal integration dimensions persist across adulthood, relate to memory and dopamine distribution, and decline with age.

The paper investigates how reduced dopamine D1 receptor availability in aging is linked to decreased functional specificity in cortico-striatal circuits and poorer memory performance.

The paper uses deep learning to predict cognitive performance from functional connectomes during different brain states and identifies the brain-cognition gap as a dopamine-related marker of cognitive vulnerability.

The paper shows that dopamine D1 receptor organization in humans aligns with a unimodal-to-transmodal functional gradient and influences network differentiation and connectivity.

The paper identifies a bi-phasic pattern of age-related dopamine D1 receptor decline, with distinct functional consequences before and after 40 years of age.