The Impact of a Western Diet High in Phosphate on the CKD-MBD in an Alport Syndrome Model
Matthew J. Williams, Hiral M. Patel, Carley B. Halling, Brian N. Finck, Keith A. Hruska
This study shows a Western high-phosphate diet worsens CKD-MBD features in Alport Syndrome mice, increasing PTH and FGF23 while reducing klotho, but does not induce vascular calcification.
Kidney360 · Jan 2, 2026Peer-reviewedPathology