Structural and biochemical insights reveal substrate-modulated nuclease activity of ComEC during DNA processing
Sophie Deselaers, Dianhong Wang, Tamino Cairoli, Pavel Afanasyev, Manuela K. Hospenthal
This study characterizes the nuclease activity of full-length ComEC during DNA processing, showing how ComEA modulates this activity to ensure fidelity in natural transformation.
bioRxiv · Apr 24, 2026 · PreprintBiochemistry