Fei Chen

Toward a networked central dogma: protein specificity reshapes molecular encounters across evolution

The paper shows that enzymatic selectivity, not collision rates, determines reaction importance across species, introducing the Networked Central Dogma as a framework connecting gene expression to cellular chemistry.

iGS: A Zero-Code Dual-Engine Graphical Software for Polygenic Trait Prediction

The paper introduces a zero-code graphical tool for polygenic trait prediction in breeding, showing linear models are robust for additive traits while machine learning and deep learning excel in complex traits.

PhyloForge: Unifying micro and macro evolution with comprehensive genomic signals

PhyloForge integrates micro and macroevolutionary data using diverse genomic signals, offering a versatile tool for phylogenetic analysis across species.

HBIcloud: An Integrative Multi-Omics Analysis Platform

HBIcloud is an online platform that integrates multi-omics tools to simplify complex data analysis for researchers without requiring extensive programming skills.

CentIER: accurate centromere identification for plant genomes with sequence specificity information

CentIER identifies centromere regions in plant genomes using sequence specificity, achieving over 90% accuracy and providing insights into centromeric retrotransposons and tandem repeats in monocots and dicots.

Pan-genome and Haplotype Map of Cultivars and Their Wild Ancestors Provides Insights into Adaptive Evolution of Cassava (Manihot esculenta Crantz)

The paper constructs nearly T2T genomes and a pan-genome of cassava cultivars and wild ancestors, revealing domestication genes and evolutionary insights.