Author

Kai Kang

National Institute of Environmental Health SciencesORCID 0000-0002-4348-3941Unclaimed ORCID profile · follow to get notified of new preprints

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Kai Kang3 papers · Beijing University of Technology

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Research Focus:deconvolution· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:eQTL / molecular QTL mapping· 1

Frequent Co-Authors

David M. UmbachiD· 2 shared Leping LiiD· 2 shared Yuanyuan LiiD· 2 shared Caizhi David HuangiD· 1 shared Igor ShatsiD· 1 shared Kaiyu Xie· 1 shared Melissa LiiD· 1 shared Qian MengiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

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9 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

David M. UmbachORCID

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3 papers

Recent·Most cited

CDSeq2 integrates individual-level cell-type expression deconvolution with recoverability-guided prioritization

Kai Kang, Kaiyu Xie

CDSeq2 improves expression deconvolution and eQTL analysis by integrating Bayesian deconvolution with prioritization of recoverable profiles in bulk RNA-seq data.

bioRxiv · Sep 21, 2026 · PreprintBioinformatics

CDSeqR: fast complete deconvolution for gene expression data from bulk tissues

Kai Kang, Caizhi David Huang, Yuanyuan Li, David M. Umbach, Leping Li

CDSeqR improves computational efficiency of CDSeq for bulk RNA-seq deconvolution and adds a function for cell type annotation using scRNA-seq data.

BMC Bioinformatics · May 24, 2021Peer-reviewedBioinformatics

A novel computational complete deconvolution method using RNA-seq data

Kai Kang, Qian Meng, Igor Shats, David M. Umbach, Melissa Li, Yuanyuan Li, Xiaoling Li, Leping Li

This paper introduces CDSeq, a computational method that estimates both cell type proportions and gene expression profiles from bulk RNA-seq data, outperforming existing methods in accuracy.

bioRxiv · Dec 14, 2018 · PreprintBioinformatics