Author

Paulo Cilas Morais Lyra Junior

Moffitt Cancer CenterORCID 0000-0002-4403-6684Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:software / tool· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Allison CreasoniD· 1 shared Álvaro N.A. MonteiroiD· 1 shared Alyssa F. PybusiD· 1 shared Chaitanya BandlamudiiD· 1 shared Chunling HuiD· 1 shared Diana L. MandelkeriD· 1 shared Fergus J. CouchiD· 1 shared Huaizhi HuangiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Allison CreasonORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 7, 2026

A Web-based software toolkit for accessible and best-practice machine learning analyses in biomedical research

Paulo Cilas Morais Lyra Junior, Junhao Qiu, Khai Dang…·Jeremy Goecks

GLEAM provides a web-based toolkit for accessible and rigorous machine learning analyses in biomedical research, producing accurate models across three tasks.

DOI 10.64898/2026.06.05.730487

machine learning (classical)software / tool

GenomicsbioRxivPreprintDec 14, 2023

Saturation genome editing-based functional evaluation and clinical classification of BRCA2 single nucleotide variants

Huaizhi Huang, Chunling Hu, Jie Na…·Fergus J. Couch

The paper functionally characterizes BRCA2 variants using saturation genome editing and classifies them clinically, finding functionally abnormal variants are associated with increased cancer risk.

5 citations

humanwhole-exome sequencing