Alyssa F. Pybus

A Web-based software toolkit for accessible and best-practice machine learning analyses in biomedical research

GLEAM provides a web-based toolkit for accessible and rigorous machine learning analyses in biomedical research, producing accurate models across three tasks.

Frequency and duration of sensory flicker controls astrocyte and neuron specific transcriptional profiles in 5xFAD mice

The paper investigates how different frequencies and durations of sensory flicker affect transcriptional profiles in 5xFAD mice, showing frequency- and duration-specific changes in immune, neuronal, and metabolic genes.

Brain rhythms control microglial response and cytokine expression via NFkappaB signaling

This study shows that specific brain rhythms alter microglial morphology and cytokine expression through NFkappaB signaling, with frequency-specific effects observed in healthy animals.

Profiling the neuroimmune cascade in 3xTg mice exposed to successive mild traumatic brain injuries

This study examines how repeated mild traumatic brain injuries affect the brain in 3xTg mice, identifying sex-specific changes in gene expression and immune responses.