Rama K. Mallampalli

The paper identifies distinct peripheral PUFA metabolites associated with different causes and severity of ARDS, suggesting potential biomarkers and therapeutic targets.

This study identifies FBXO24 as the E3 ligase regulating FoxP1 ubiquitination and stability, revealing bidirectional regulation between the ligase and its substrate.

This study examines how glycosylation mutations in the NTD of the SARS-CoV-2 XEC variant affect neutralizing antibody responses, cell-cell fusion, and spike stability.

This study evaluates neutralization, infectivity, and stability of JN.1-derived SARS-CoV-2 subvariants, finding that DelS31 mutation in the NTD reduces nAb titers, impairs infectivity, and increases spike stability.

This study identifies endothelial TLR3 insufficiency as a mechanism underlying SARS-CoV-2-induced lung vascular remodeling and suggests TLR3 agonists as a potential therapeutic strategy.