Reciprocal Regulation Between the SCFFBXO24 Ubiquitin E3 Ligase and FoxP1 Protein
A. Maloy, Sydney Walter, A. Mascilli, David C. Klein, Santana M. Lardo, James David Londino, Toru Nyunoya, John F. McDyer, Mianen Sun, Xuemei Zeng, Nathan A. Yates, Pamela S. Cantrell, Sarah J. Hainer, Rama K. Mallampalli, Divay Chandra
This study identifies FBXO24 as the E3 ligase regulating FoxP1 ubiquitination and stability, revealing bidirectional regulation between the ligase and its substrate.
bioRxiv · May 23, 2025 · PreprintMolecular Biology