GeneticsFrontiers in ImmunologyPeer-reviewed
Regulatory architecture of the RCA gene cluster captures an intragenic TAD boundary, CTCF-mediated chromatin looping and a long-range intergenic enhancer
Jessica Cheng, Joshua S. Clayton, Rafael D. Acemel…·Daniela Ulgiati
The paper identifies regulatory elements and chromatin structures in the RCA gene cluster, revealing long-range interactions and a TAD boundary within CR1 that influence gene expression and autoimmune disease susceptibility.