Systems Biology Analysis Using A Genome-Scale Metabolic Model Shows That Phosphine Triggers Global Metabolic Suppression In A Resistant Strain Of C. elegans
Li Ma, Angelo Chan, Jake P. N. Hattwell, Paul R. Ebert, Horst Joachim Schirra
The paper uses a genome-scale metabolic model and metabolomics to show phosphine resistance in C. elegans is linked to hypometabolic adaptation via DLD.
bioRxiv · May 31, 2017 · PreprintSystems Biology