Author

Lichun Zhang

Chinese University of Hong KongORCID 0000-0002-4441-2176Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 3 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:DNA methylation· 3 Organism:human· 3 Research Focus:spatial domain detection· 3 Research Focus:clustering· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2

Frequent Co-Authors

Ben Tin Yan Wong· 3 shared Eldric Pui Lam Tsoi· 3 shared Hei Ming LaiiD· 3 shared Yuqi TaniD· 3 shared Brian Pak Shing PangiD· 2 shared Joshua Jing Xi LiiD· 2 shared King Ngai ChowiD· 2 shared Bei HuangiD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBioengineering

Ben Tin Yan Wong

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

REZCUE: Rescuing 3D spatial omics from archived FFPE tissue

Lichun Zhang, William Chi Shing Cho, Joshua Jing Xi Li, Brian Pak Shing Pang, Ben Tin Yan Wong, Eldric Pui Lam Tsoi, Yuqi Tan, Hei-Ming Lai

REZCUE enables 3D spatial multi-omic analysis of archived FFPE tissue by preserving nucleic acids and proteins for subsequent assays.

bioRxiv · Oct 7, 2026 · PreprintBioengineering

COLOR-3D: a versatile tool for revealing novel 3D histological features

King Ngai Chow, Eldric Pui Lam Tsoi, Ben Tin Yan Wong, Lichun Zhang, Tin Wai Ho, Yuqi Tan, J J Li, Hei Ming Lai

COLOR-3D improves 3D histology by enhancing dye penetration and enables quantitative analysis of tissue morphology and aging-related changes in mouse liver.

bioRxiv · May 27, 2026 · PreprintPathology

Universal nucleic acid preservation in biological fluids with boron clusters

Brian Pak Shing Pang, Lichun Zhang, Ben Tin Yan Wong, Mike P Williamson, Hei Ming Lai

This paper introduces [B12H12]2- as a broad-spectrum nuclease inhibitor that preserves nucleic acids in biological fluids at room temperature for extended periods.

bioRxiv · Jan 14, 2026 · PreprintBioengineering

INSIHGT: Accessible multimodal systems biology with quantitative molecular phenotyping in 3D

Chun Ngo Yau, Jacky Tin Shing Hung, Robert A. A. Campbell, Thomas Chun Yip Wong, Bei Huang, Ben Tin Yan Wong, King Ngai Chow, Lichun Zhang, Eldric Pui Lam Tsoi, Yuqi Tan, Joshua Jing Xi Li, Yun Kwok Wing, H. M. Lai

The paper introduces INSIHGT, a 3D spatial biology method for multi-modal molecular phenotyping, and demonstrates its application in mapping cellular structures and identifying novel cell types in human and mouse tissues.

Nature Communications · Dec 30, 2024Peer-reviewedBioengineering