Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks
Quan Jiang, Ling-Xiao Shao, Shenqin Yao…·Alex C. Kwan
This study shows psilocybin alters large-scale cortical network connectivity in mice by strengthening inputs from perceptual and medial regions and weakening cortico-cortical loops, dependent on drug-evoked spiking activity.