Molecular BiologyJCI InsightPeer-reviewed
Sustained Yap/Taz activation promotes aberrant alveolar epithelial cell differentiation and drives persistent fibrotic remodeling
Isabella P. Gaona, A. Scott McCall, Natalie M. Geis…·Jason J. Gokey
This study shows sustained Yap/Taz activation in alveolar epithelial cells leads to fibrotic remodeling and impaired repair, with potential therapeutic implications.