GenomicsGenetic EpidemiologyPeer-reviewed
TWO-SIGMA: a novel TWO-component SInGle cell Model-based Association method for single-cell RNA-seq data
Eric C. Van Buren, Ming Hu, Chen Weng…·Yun Li
TWO-SIGMA is a single-cell RNA-seq differential expression method that handles drop-out, overdispersion, and within-sample correlation, outperforming existing methods in simulations and real data.
10 citations