NeurosciencebioRxivPreprint
Cerebrospinal fluid YWHAG:NPTX2 ratio predicts clinical severity and future phenoconversion in frontotemporal lobar degeneration
Hamilton Se‐Hwee Oh, Joshua D. Downer, Connor D. Dietz…·Scott J. Russo
The paper identifies the CSF YWHAG:NPTX2 ratio as a biomarker for predicting clinical severity and phenoconversion in FTLD, showing strong correlation with disease progression and improved trial design potential.
DOI 10.64898/2026.08.22.746470