ImmunologybioRxivPreprint
Engineering programmable CAR-T cells with tunable controls as fail-safe mechanisms during cancer immunotherapy
Mikail Dogan, Lina Kozhaya, Lindsey Placek…·Derya Unutmaz
This study develops a synthetic biology toolbox to engineer CAR-T cells with tunable controls, enabling safe and effective cancer immunotherapy through fail-safe mechanisms.
DOI 10.1101/2024.07.09.602762